The Susan G. Komen Foundation supports breast-cancer research directly, and also gives community grants for things like screenings, support groups, education efforts, and other needs. It's a great organization that makes good use of the money they raise.
If anyone is interested in supporting me in the Jazzerthon and donating to an excellent (and tax deductible) cause, the Komen folks have arranged for us to accept online donations through their "Race for the Cure" site. Here's my donations page.